Search

Search

Esta página ha sido traducida por una máquina. Otras páginas pueden seguir apareciendo en inglés. View in English

Home
...
Áreas de investigación Ciencias Biomédicas y Clínicas Oncología y carcinogénesis Objetivos moleculares
Áreas de investigación
Ciencias Biomédicas y Clínicas
Oncología y carcinogénesis
Objetivos moleculares
Descubrimiento, seguridad preclínica y caracterización de la eficacia de SMAC mimetic S-016-1348 como un potencial terapéutico contra el cáncer

Descubrimiento, seguridad preclínica y caracterización de la eficacia de SMAC mimetic S-016-1348 como un potencial terapéutico contra el cáncer

Abhipsa Sinha ¹, Mushtaq Ahmad Nengroo ¹, Rafat Ali ², Afsar Ali Khan ², Himangsu Sekhar Dutta ², Akhilesh Singh ¹, Krishan Kumar Saini ³, Kiran Tripathi ¹, Roshan Katekar ⁴, Shivam Rathaur ⁴, Jayanti Vaishnav ⁵, Gajendra Singh ⁵, Mohammad Afsar ⁶, Sanjeev Meena ¹, Anjna Sahu ⁵, Abhishek Kumar Shaw ², Kulranjan Singh ⁷, Ravishankar Ramachandran ⁸, Manish Kumar Chourasia ⁹, Manoj Barthwal ¹⁰, Prem Narayan Yadav ¹¹, Aravind Singh Kshatri ¹¹, Radha Rangarajan ¹², Aamir Nazir ¹¹, Ravi Sankar Ampapathi ¹³, Jiaur Rahaman Gayen ⁹, Dipankar Koley ¹⁴, Wahajul Haq ¹⁴, Dipak Datta ³

Abhipsa Sinha ¹, Mushtaq Ahmad Nengroo ¹, Rafat Ali ²

¹Division of Cancer Biology Division, CSIR-Central Drug Research Institute (CDRI), Lucknow 226031, India.
²Medicinal Process Chemistry, CDRI, Lucknow 226031, India.
³Division of Cancer Biology Division, CSIR-Central Drug Research Institute (CDRI), Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.
⁴Pharmaceutics & Pharmacokinetics, CDRI, Lucknow 226031, India.
⁵Sophisticated Analytical Instrument Facility & Research, CDRI, Lucknow 226031, India.
⁶Biochemistry and Structural Biology Division, CDRI, Lucknow 226031, India.
⁷Department of Endocrine Surgery, King George's Medical University, Lucknow, Uttar Pradesh 226003, India.
⁸Biochemistry and Structural Biology Division, CDRI, Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.
⁹Pharmaceutics & Pharmacokinetics, CDRI, Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.
¹⁰Pharmacology Division, CDRI, Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.
¹¹Division of Neuroscience and Ageing Biology, CDRI, Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.
¹²Division of Molecular Microbiology and Immunology, CDRI, Lucknow 226031, India.
¹³Sophisticated Analytical Instrument Facility & Research, CDRI, Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.
¹⁴Medicinal Process Chemistry, CDRI, Lucknow 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201002, India.

⁰Division of Cancer Biology Division, CSIR-Central Drug Research Institute (CDRI), Lucknow 226031, India.

Molecular Therapy : the Journal of the American Society of Gene Therapy +

|

4 de enero de 2026

|

4 de enero de 2026

Videos de Experimentos Relacionados

Contact us if these videos are not relevant.

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells

Published on: March 28, 2021

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

Published on: November 12, 2019

See all related videos

Resumen

No abstract available on PubMed

Videos de Experimentos Relacionados

Contact us Si estos videos no son relevantes.

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells

Published on: March 28, 2021

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

Published on: November 12, 2019

See all related videos

Videos de Conceptos Relacionados

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Share

X
Facebook
LinkedIn
YouTube

ABOUT JoVE

Overview
Leadership
Blog
JoVE Help Center

AUTHORS

Publishing Process
Editorial Board
Scope & Policies
Peer Review
FAQ
Submit

LIBRARIANS

Testimonials
Subscriptions
Access
Resources
Library Advisory Board
FAQ

RESEARCH

JoVE Journal
Methods Collections
JoVE Encyclopedia of Experiments
Archive

EDUCATION

JoVE Core
JoVE Business
JoVE Science Education
JoVE Lab Manual
Faculty Resource Center
Faculty Site

Terms & Conditions of Use
Privacy Policy
Policies