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El hidrogel de wedelolactona sensible a ROS promueve la reparación del disco intervertebral al interrumpir el

Zimei Wu1,2,3, Yan Xu1,2, Lang Qin1

  • 1Department of Orthopedic Surgery, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 5, 2026
PubMed
Resumen

No abstract available in PubMed .

Palabras clave:
NF-κBLCN2 ciclo de retroalimentaciónHidrogeles sensibles a las ROSremodelación de la matriz extracelularDegeneración de los discos intervertebralesAcetilcolina y sus derivados

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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