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Un nanoamplificador de ROS en cascada para la terapia sonoquimiodinámica mejorada del osteosarcoma

Panfeng Wang1, Hongrui Wang1, Dayuan Xu2

  • 1Department of Orthopedics, Changhai Hospital, Naval Medical University, Shanghai, China.

Advanced healthcare materials
|January 5, 2026
PubMed
Resumen

No abstract available in PubMed .

Palabras clave:
RuO2Cuadros metálicos orgánicos basados en Zrnanoamplificador de ROS en cascadaTerapia quimiodinámicaTerapia sonodinámica

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Amplifying Signals via Enzymatic Cascade01:22

Amplifying Signals via Enzymatic Cascade

When a ligand binds to a cell-surface receptor, the receptor's intracellular domain changes shape, which may either activate its enzyme function or allow its binding to other molecules. The initial signal is amplified by most signal transduction pathways. This means that a single ligand molecule can activate multiple molecules of a downstream target. Proteins that relay a signal are most commonly phosphorylated at one or more sites, activating or inactivating the protein. Kinases catalyze the...
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