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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Los genes patógenos relacionados con la senescencia celular en los trastornos del sueño: un estudio de aleatorización

Jinying Li1,2,3, Suchun Ding3, Xingbo Zhang4

  • 1Department of anesthesiology, Affiliated Zhongshan hospital of Dalian University, Dalian, 116622, China.

European archives of psychiatry and clinical neuroscience
|January 5, 2026
PubMed
Resumen

No abstract available in PubMed .

Palabras clave:
Envejecimiento celularLocalizaciónSomnolencia durante el díaEl insomnioAnálisis de aleatorización mendelianaMultiómicaSíndrome de apnea del sueñoTrastornos del sueño

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