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Nefrolitiasis donada: análisis de casos y estudio comparativo

Maxwell Sandberg1, Mark Xu1, Randall Bissette1

  • 1Department of Urology, Wake Forest Baptist Medical Center, Winston Salem, NC 27101, USA.

The Canadian journal of urology
|January 7, 2026
PubMed
Resumen
Este resumen es generado por máquina.

La nefrolitiasis donada, o cálculos renales en riñones de donante fallecido (DF), es muy rara en trasplantes de riñón. Este estudio encontró resultados favorables en pacientes y injertos, sugiriendo que el trasplante es viable incluso con cálculos conocidos.

Palabras clave:
nefrolitotomía percutánea de riñón de donante fallecidonefrolitiasiscálculotrasplante

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Área de la Ciencia:

  • Nefrología
  • Cirugía de Trasplantes
  • Urología

Sus antecedentes:

  • La nefrolitiasis donada es una complicación rara en el trasplante renal de donante fallecido (DF).
  • Existe investigación limitada, carente de pautas establecidas para el manejo de cálculos renales en donantes.
  • Esta variabilidad afecta la selección de riñones de donantes y la atención al receptor.

Objetivo del estudio:

  • Determinar la frecuencia de nefrolitiasis donada en receptores de trasplante renal de DF.
  • Analizar los resultados de pacientes y injertos en receptores con cálculos renales donados.
  • Evaluar la seguridad y viabilidad del trasplante de riñones con cálculos preexistentes.

Principales métodos:

  • Revisión retrospectiva de trasplantes renales de DF y atención postoperatoria en el Wake Forest Baptist Medical Center (1979-2025).
  • Identificación de cálculos donados descubiertos durante o dentro de las dos semanas posteriores al trasplante.
  • Comparación del tamaño del cálculo entre pacientes tratados y vigilados; análisis de los resultados de pacientes y injertos.

Principales resultados:

  • Ocho de 4723 trasplantes renales de DF (0,2%) tuvieron nefrolitiasis donada.
  • El tamaño mediano del cálculo fue de 8 mm
  • el 38% de los pacientes recibieron tratamiento, el 62% se sometieron a vigilancia.
  • Ocurrió un fallo del injerto en el 25% de los receptores, con un caso relacionado con el tratamiento del cálculo.

Conclusiones:

  • La nefrolitiasis donada es excepcionalmente rara en el trasplante renal de DF.
  • Los resultados favorables de pacientes e injertos respaldan la viabilidad del trasplante de riñones de DF con cálculos conocidos.
  • La investigación adicional puede refinar las estrategias de manejo para esta rara condición.