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Vasculitis por Complejos Inmunes Localizada de Pequeños Vasos que se Presenta como Miositis Unilateral Después de la
Mariam Zeidan1, Rita Abou Zeid2, Hajar Alhusani2
1Faculty of Medicine, American University of Beirut, Beirut, LBN.
Cureus
|January 7, 2026
Resumen
Este estudio de caso detalla la primera instancia de vasculitis unilateral de pequeños vasos por complejos inmunes (VPCV) que afecta los músculos de las piernas, desencadenada por la infección por el virus de la Hepatitis A (VHA). El tratamiento inmunosupresor rápido condujo a la remisión, destacando la importancia del diagnóstico temprano.
Sus antecedentes:
- La vasculitis de pequeños vasos por complejos inmunes (VPCV) implica la deposición de complejos inmunes en los vasos sanguíneos pequeños, lo que lleva a inflamación y necrosis.
- El virus de la Hepatitis A (VHA) es un desencadenante poco común de vasculitis, a diferencia de la hepatitis B y C.
- La miositis vasculítica, la inflamación de los músculos debido a la vasculitis, es típicamente bilateral y simétrica, con pocos informes de enfermedad unilateral o limitada a los músculos.
Conclusiones:
- Este caso establece el primer vínculo entre la miositis vasculítica por complejos inmunes unilateral con biopsia confirmada y la infección por VHA.
- Subraya la importancia de considerar la miositis vasculítica en el diagnóstico diferencial de la hinchazón focal de las extremidades con inflamación sistémica.
- La terapia inmunosupresora temprana es crucial para resultados favorables en esta rara condición.
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