Video Experimental Relacionado

Updated: Jan 13, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Published on: August 15, 2025

Progreso de la investigación en la composición de oligosacáridos en fármacos tónicos y su eficacia

Xiao-Li Ma¹, Xiao-Yan Lan², Li Zhou²

¹Tianjin University of Traditional Chinese Medicine Tianjin 301617, China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

|January 8, 2026

Resumen

Los oligosacáridos en las hierbas tónicas muestran diversos beneficios para la salud, incluidos efectos antidepresivos y antitumorales. La investigación avanza en su composición, estructura y actividad en la Medicina Tradicional China (MTC).

Área de la Ciencia:

Fitoquímica
Farmacología
Medicina Tradicional China (MTC)

Sus antecedentes:

Los oligosacáridos, polímeros de carbohidratos de bajo peso molecular, son componentes activos clave en las hierbas tónicas.
Estos compuestos exhiben actividades farmacológicas significativas, incluidas funciones antidepresivas, antitumorales e inmunomoduladoras.
La investigación sobre oligosacáridos en la MTC tónica está ganando impulso debido a los avances en las técnicas analíticas y de evaluación.

Objetivo del estudio:

Revisar la composición, estructura y efectos farmacológicos de los oligosacáridos en la Medicina Tradicional China (MTC) tónica.
Destacar los avances en la investigación de oligosacáridos de hierbas tónicas específicas como Panax ginseng, Morinda officinalis y Codonopsis pilosula.
Proporcionar una referencia para futuros estudios sobre la relación estructura-actividad y el control de calidad de los oligosacáridos en la MTC.

Principales métodos:

Revisión de literatura centrada en estudios de oligosacáridos en la MTC tónica.
Análisis de la composición y características estructurales de estos oligosacáridos.
Examen de los efectos farmacológicos reportados y la investigación de control de calidad.

Principales resultados:

Los oligosacáridos de las hierbas tónicas poseen diversas actividades farmacológicas.
Se han logrado avances significativos en la investigación de oligosacáridos en Panax ginseng, Morinda officinalis y Codonopsis pilosula.
La investigación actual se centra en la composición, estructura, actividad y control de calidad.

Conclusiones:

Los oligosacáridos son componentes bioactivos vitales en la MTC tónica con un amplio potencial terapéutico.
La investigación adicional sobre las relaciones estructura-actividad y métodos de control de calidad robustos es crucial.
Esta revisión proporciona una base para avanzar en la comprensión científica y la aplicación de los oligosacáridos en la MTC.

Palabras clave:

oligosacárido efecto farmacológico control de calidad característica estructural hierba tónica

Más Videos Relacionados

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Published on: February 17, 2017

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota

Published on: May 23, 2025

Videos de Conceptos Relacionados

Oligosaccharide Assembly

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...

Drugs Affecting GI Tract Motility: Other Laxatives

Drugs Affecting GI Tract Motility: Other Laxatives

Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...

Biosynthesis of Polysaccharides

Biosynthesis of Polysaccharides

Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...

Protein Glycosylation

Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
Glycosylation occurs in...