Video Experimental Relacionado

Updated: Jan 13, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
08:35

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

6.3K

Polialadenilación Alternativa Específica de Etapa Durante la Diferenciación Neural Humana Revelada por Secuenciación

Zheqi Lou1, Xianyan Zeng1,2, Tinghui Jiang1

  • 1College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.

Biology
|January 10, 2026
PubMed
Resumen

Este estudio revela nuevos conocimientos sobre la polialadenilación alternativa (APA) durante la diferenciación neural de células madre embrionarias humanas (hESC). La investigación identifica miles de nuevos transcritos y sitios de poli(A), mejorando nuestra comprensión de la regulación del destino celular.

Palabras clave:
Tecnologías Oxford Nanoporepolialadenilación alternativapolialadenilación alternativa de exonescélulas madre embrionarias humanaspolialadenilación alternativa intrónicadiferenciación neuralsecuenciación de lectura corta

Más Videos Relacionados

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay11:22

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay

Published on: August 26, 2018

9.2K
Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes10:48

Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes

Published on: April 12, 2015

10.5K

Videos de Conceptos Relacionados

Alternative RNA Splicing02:18

Alternative RNA Splicing

Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
24.6K
RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
11.7K