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Videos de Conceptos Relacionados

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
219
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

227
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
227
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Aging01:26

Aging

580
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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Video Experimental Relacionado

Updated: Jan 13, 2026

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
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Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

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Abordar la desnutrición en la población de edad avanzada

Patrizia D'Amelio1

  • 1Service of Geriatric Medicine & Geriatric Rehabilitation, Department of Medicine, University of Lausanne Hospital (CHUV), 1011 Lausanne, Switzerland.

Nutrients
|January 10, 2026
PubMed
Resumen

La desnutrición en adultos mayores es un problema importante que afecta el envejecimiento saludable. Abordar este desafío nutricional es crucial para mejorar los resultados de salud en la población de edad avanzada.

Palabras clave:
desnutriciónadultos mayoresenvejecimiento saludablesalud públicaintervención nutricional

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Área de la Ciencia:

  • Gerontología
  • Salud Pública
  • Ciencia de la Nutrición

Sus antecedentes:

  • La desnutrición en adultos mayores es un problema de atención médica prevalente y grave.
  • Afecta significativamente el envejecimiento saludable y aumenta la utilización de la atención médica.
  • La identificación e intervención tempranas son esenciales para mejores resultados de salud.

Objetivo del estudio:

  • Destacar la naturaleza crítica de la desnutrición en las personas mayores.
  • Subrayar su impacto en el envejecimiento saludable.
  • Enfatizar la necesidad de una mayor atención y acción.

Principales métodos:

  • Revisión de la literatura existente sobre desnutrición geriátrica.
  • Análisis de datos de atención médica relacionados con el estado nutricional en adultos mayores.
  • Síntesis de evidencia sobre las consecuencias de la desnutrición.

Principales resultados:

  • La desnutrición está muy extendida entre los adultos mayores.
  • Está relacionada con numerosos resultados adversos para la salud, como un aumento de la morbilidad y la mortalidad.
  • Tanto la desnutrición como la sobrealimentación plantean riesgos.

Conclusiones:

  • La desnutrición en adultos mayores requiere atención urgente por parte de los proveedores de atención médica y los responsables políticos.
  • Se necesitan estrategias efectivas de prevención y tratamiento para promover un envejecimiento saludable.
  • Se justifica una mayor investigación para desarrollar intervenciones específicas.