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Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
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Los investigadores exploraron la síntesis total de darobactina A, un antibiótico eficaz contra bacterias Gram-negativas. Los pasos clave incluyeron nuevas síntesis de indol y estrategias de macrociclación, lo que proporcionó información valiosa sobre los mecanismos de reacción.

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