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Updated: Jan 13, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

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El embarazo como prueba de estrés: Replantear el cuarto trimestre como una ventana de intervención y medicina de

Athina Samara¹, Asma Khalil²

¹FUTURE, Center for Functional Tissue Reconstruction, Department of Biomaterials, University of Oslo, Oslo, Norway; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Med (New York, N.Y.)

|January 10, 2026

Abstract:

Pregnancy triggers profound physiological changes, yet postpartum recovery remains under-recognized despite its predictive significance for lifelong health. The fourth trimester offers a critical window to detect cardiometabolic, immunological, and mental-health vulnerabilities. We propose a precision postpartum medicine framework integrating human-relevant models, longitudinal multi-omics, and AI-enabled risk stratification to transform postpartum care.

Palabras clave:

medicina de precisión posparto cuarto trimestre salud materna IA multiómica medicina de precisión salud posparto recuperación posparto salud de por vida gestión proactiva

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