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Updated: Jan 13, 2026

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Identificación de relaciones causales genotipo-fenotipo para tríos de padres e hijos muestreados en población

Yushi Tang1, Irineo Cabreros2, John D Storey1

  • 1Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.

Genetic epidemiology
|January 12, 2026
PubMed
Resumen

La transmisión genética ofrece aleatorización natural para identificar loci genéticos causales. Nuevos métodos como la prueba de la media de transmisión (TMT) aprovechan los datos de tríos de padres e hijos para la estimación de efectos causales, complementando los enfoques existentes.

Palabras clave:
inferencia causalvinculación causalasociaciones genómicasresultados potencialesexperimentos aleatoriosdesequilibrio de transmisiónprueba de la media de transmisión

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