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Updated: Jan 13, 2026

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Culture and Co-Culture of Mouse Ovaries and Ovarian Follicles
Published on: March 17, 2015
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La hipoxantina participa en la promoción de la activación de los folículos primordiales de ratón†
Ying Wei1, Weiyong Wang1, Huiyu Liu1
1The Innovation Centre of Ministry of Education for Development and Diseases, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Biology of reproduction
|January 12, 2026
Abstract:
In each wave, only a small portion of primordial follicles are selectively activated into the growing follicular pool, and the majority of primordial follicles remain in a relatively quiescent state. Hypoxanthine is present in the follicular fluid with high concentrations and inhibits phosphodiesterase (PDE) activity. $$ contribute to the promotion of the cyclic activation of primordial follicles.

