Video Experimental Relacionado

Updated: Jan 14, 2026

Simple and Efficient Production and Purification of Mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis Studies

Simple and Efficient Production and Purification of Mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis Studies

Published on: October 27, 2016

Relación de Ratios de Mielina g: El Modelo Está en los Detalles

Alexander Gow^1,2,3

¹Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.

|January 12, 2026

Resumen

Este estudio evalúa métodos para medir la relación g de la mielina utilizando microscopía electrónica. Un método ampliamente utilizado es defectuoso, lo que podría llevar a conclusiones inexactas sobre la integridad de la sustancia blanca y la neuropatología.

Conclusiones:

El modelo canónico de la relación g requiere una reevaluación debido a su discordancia con los datos fundamentales.
Las relaciones g precisas derivadas de ME son cruciales para calibrar técnicas de imagen no invasivas como la RM.
La RM muestra potencial para la evaluación clínica de la mielina, particularmente en tractos de sustancia blanca organizados.

Palabras clave:

modelo de unidad axomielínica análisis exploratorio de datos ratio gc g’cline simulaciones

Más Videos Relacionados

Preparation and Immunostaining of Myelinating Organotypic Cerebellar Slice Cultures

Preparation and Immunostaining of Myelinating Organotypic Cerebellar Slice Cultures

Published on: March 20, 2019

Coherent Anti-Stokes Raman Spectroscopy CARS Application for Imaging Myelination in Brain Slices

Coherent Anti-Stokes Raman Spectroscopy CARS Application for Imaging Myelination in Brain Slices

Published on: July 22, 2022

Videos de Conceptos Relacionados

Nervous Tissue: Myelin

Nervous Tissue: Myelin

The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...