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Updated: Jan 14, 2026

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
Published on: September 1, 2022
Un microsistema optoelectrónico autónomo 43 μm × 269 μm adaptable a la luz para la grabación neuronal
Abstract:
We present a 43 $μ$m × 269 μm tetherless neural recording microsystem in which the CMOS bulk is forward biased to utilize silicon junctions as a photovoltaic source. Our microsystem, forward-bulk microscale optoelectronic tetherless electrode (FB-MOTE), can operate with as low as 0.2 $μ$A at 0.317 V and can withstand light intensity up to 1200 $μ$W/mm2, and is power-adaptive: the higher available power increases the system bandwidth while maintaining the input-referred integrated noise. To balance between adaptability and stability, we have designed our amplifier to take up most of the additional power, hence acting like a regulator, while the other circuit blocks are PTAT-biased to remain relatively stable across available power levels. The amplified neural signals are pulse position modulated (PPM) and optically transmitted through an AlGaAs microscale light emitting diode ($μ$LED) for its information per-photon efficiency, where the $μ$LED driver is designed to maximize the emission-to-area ratio. Finally, we discuss various light-induced effects observed in measurements and introduce a simulation methodology to account for such effects and its limitations. Our forward-bulk CMOS microsystem provides an approach that can effectively harness and account for the available light in optoelectronic systems design.

