Video Experimental Relacionado

Updated: Jan 15, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Descifrando el mecanismo de modificación por O-carbamoylation en la biosíntesis de Venturicidina A

Qi Chen1, Chunya Xie1, Jiaozhuang Liu1

  • 1School of Life Sciences, Anhui Medical University, Hefei 230032, China.

Organic letters
|January 13, 2026
PubMed
Resumen

La Venturicidina Deaminasa B (VtdB) es una O-carbamoyltransferasa esencial que convierte la venturicidina B en A. Estudios estructurales revelan la unión del sustrato en un bolsillo hidrofóbico, con His35 crucial para la catálisis.

Palabras clave:
Venturicidina AbiosíntesisO-carbamoylationVenturicidina Deaminasa BVtdBO-carbamoyltransferasacatálisisestructura cristalinabolsillo hidrofóbicoHistidina 35d-olivose-glicosiladosmacrólidos

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