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Updated: Jan 17, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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La E3 ligasa RNF5 facilita la replicación viral al suprimir las respuestas inmunitarias innatas en el mero

Yanqi Zhao1, Xiaohui Zheng1, Siting Wu1

  • 1College of Marine Sciences, South China Agricultural University, Guangzhou, 510642, China.

Fish & shellfish immunology
|January 14, 2026
PubMed
Resumen

Se descubrió que la proteína del anillo 5 (RNF5) en el pez mero mejora la replicación del iridovirus del mero de Singapur (SGIV) y del virus de la necrosis nerviosa del mero con manchas rojas (RGNNV). Esta proteína suprime las respuestas inmunitarias antivirales, lo que ayuda a la patogenia de los virus de peces.

Palabras clave:
Epinephelus coioidesRGNNVRNF5SGIVReplicación viral

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