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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Optimización de los resultados informados por los pacientes para la sarcoidosis

Vivienne Kahlmann1, Donald Simon2, Marlies S Wijsenbeek1

  • 1Centre of Excellence for Interstitial Lung Diseases and Sarcoidosis, Department of Respiratory Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

Current opinion in immunology
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Las medidas de resultados informados por los pacientes (PROMs) son cruciales para evaluar a los pacientes con sarcoidosis

Palabras clave:
Medidas de resultados informados por el pacienteSarcoidosisCalidad de vidaPropiedades psicométricasDesarrollo de PROMs

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Área de la Ciencia:

  • Medicina Pulmonar
  • Reumatología
  • Inmunología

Sus antecedentes:

  • La sarcoidosis presenta diversos síntomas que afectan la calidad de vida (QoL) del paciente.
  • La QoL es una prioridad de tratamiento clave para los pacientes con sarcoidosis.
  • Medir la experiencia de los síntomas del paciente es vital pero desafiante.

Objetivo del estudio:

  • Revisar las medidas de resultados informados por el paciente (PROMs) genéricas y específicas de la enfermedad comúnmente utilizadas para la sarcoidosis.
  • Resumir las propiedades psicométricas de estos PROMs.
  • Discutir las limitaciones y las direcciones futuras para el uso de PROMs en la sarcoidosis.

Principales métodos:

  • Revisión de la literatura de PROMs en sarcoidosis.
  • Análisis de las propiedades psicométricas (validez, confiabilidad, capacidad de respuesta).
  • Síntesis de los hallazgos sobre la aplicación de PROMs en ensayos clínicos y en la práctica.

Principales resultados:

  • Visión general de los PROMs genéricos y específicos de la sarcoidosis de uso frecuente.
  • Resumen de las fortalezas y debilidades psicométricas de las medidas disponibles.
  • Identificación de lagunas y oportunidades para el desarrollo e implementación de PROMs.

Conclusiones:

  • Los PROMs son herramientas esenciales para evaluar la experiencia del paciente con sarcoidosis y la efectividad del tratamiento.
  • Es necesaria una cuidadosa selección de PROMs basada en propiedades psicométricas.
  • La investigación futura debe centrarse en refinar los PROMs existentes y desarrollar otros nuevos adaptados a la sarcoidosis.