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Progreso de la investigación sobre la modificación por lactilación en la patogénesis de la osteoartritis

Yuangang Wu1, Kaibo Sun1, Yang Ding1

  • 1Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
|January 15, 2026
PubMed
Resumen

La modificación por lactilación, impulsada por el lactato, desempeña un papel clave en la patogénesis de la osteoartritis (OA) al alterar la expresión génica y las funciones celulares. La comprensión de este proceso epigenético ofrece nuevas dianas terapéuticas para la OA.

Palabras clave:
modificación por lactilacióncondrocitosepigenéticacélulas inmunitariasosteoartritissinoviocitos

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