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Updated: Jan 18, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
Published on: January 17, 2025
Abscesos prostáticos como causa de bacteriemia persistente por Staphylococcus aureus
Valeria Ferrando-Mérida1, Marina Machado2, Carmen Cuenca3
1Clinical Microbiology and Infectious Disease Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.
Introduction:
Persistent Staphylococcus aureus bacteremia (SAB) is associated with high mortality and requires prompt identification and control of the infectious source. Prostatic abscesses, though rare, are an underrecognized cause of persistent SAB, especially in patients with urinary symptoms and comorbidities.
Methods:
We present two cases of persistent methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia in which no initial focus was identified despite extensive evaluation. Further investigation led to the diagnosis of prostatic abscesses as the underlying source.
Results:
Both patients underwent transurethral drainage of the abscesses in combination with prolonged antibiotic therapy. This combined approach resulted in resolution of the bacteremia and favorable clinical outcomes.
Conclusions:
Prostatic abscesses should be considered in the differential diagnosis of persistent SAB, particularly in patients with suggestive urinary symptoms or risk factors. Timely recognition and appropriate source control through surgical drainage and antibiotics are essential for achieving clinical cure.
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