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Proteína tipo colágeno multifuncional como vehículo de terapia génica para aplicaciones biomédicas

Gopalan Akilandeswari¹, Niraikulam Ayyadurai¹

¹Division of Biochemistry and Biotechnology, Council of Scientific and Industrial Research (CSIR) - Central Leather Research Institute, Chennai, Tamil Nadu, India.

Cell biochemistry and function

|January 16, 2026

Resumen

Los investigadores desarrollaron una novedosa fusión de proteínas, proteína tipo colágeno-proteína adhesiva de mejillón (CLP-MAP), para la terapia génica. Este sistema biocompatible une y administra eficazmente el ADN, mostrando potencial como vehículo de administración génica no viral.

Conclusiones:

La proteína de fusión CLP-MAP es un agente de unión al ADN estable y eficaz.
CLP-MAP exhibe biocompatibilidad y potencial como un sistema novedoso y no viral de administración de genes.
Esta proteína de ingeniería promete avanzar en las aplicaciones de terapia génica.

Palabras clave:

proteína tipo colágeno unión de ADN proteína de fusión proteína adhesiva de mejillón

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