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Updated: Jul 1, 2026

Monitoring Protein Adsorption with Solid-state Nanopores

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Published on: December 2, 2011

Identificación de proteínas de longitud completa con resolución de un solo aminoácido mediante nanoporos

Andrea Bonini, Chunzhe Lu, Luca Mantovanelli

bioRxiv : the preprint server for biology

|January 16, 2026

Abstract:

Nanopore-based technologies show promise in single-molecule protein sequencing. By using an unfoldase and a nanopore with enhanced electroosmotic flow, here we show the continuous identification of generic proteins during single nanopore passes. This approach enables the recording of differences in charge and size from single amino acid substitutions compared to reference signals, paving the way for single-molecule protein sequencing and high-throughput proteomics.

Palabras clave:

nanoporos secuenciación de proteínas proteómica proteínas de molécula única resolución de aminoácidos

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