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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Video Experimental Relacionado

Updated: Jan 18, 2026

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

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Ingeniería de Células T con CAR Totalmente Humanas Optimizadas para la Funcionalidad B7-H3 para una Terapia Mejorada

Pradip Bajgain, Yang Feng, Mariela Puebla

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    Resumen
    Este resumen es generado por máquina.

    Se desarrollaron anticuerpos totalmente humanos específicos de B7-H3 para la terapia de células T con receptores de antígenos quiméricos (CAR). Estas nuevas células T con CAR demostraron una eficacia y seguridad superiores en modelos de tumores sólidos en comparación con las terapias existentes.

    Palabras clave:
    terapia de células T con CARB7-H3tumores sólidosanticuerpos totalmente humanosinmunogenicidadingeniería de proteínasoncologíabiotecnología

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