Video Experimental Relacionado

Updated: Jan 18, 2026

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
08:37

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog

Published on: November 5, 2014

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Consecuencias celulares, sustratos de citrulinación y antigenicidad resultantes de PAD4 salvaje y dirigida en la

Sophie Kong, Trenton M Peters-Clarke, Corleone S Delaveris

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    Resumen

    La proteína desiminasa de arginina-4 (PAD4) causa cambios y migración celular, lo que podría impulsar el cáncer. Nuevos métodos identificaron numerosos sustratos de PAD4, revelando información sobre enfermedades autoinmunes como las que generan anticuerpos contra proteínas citrulinadas (ACPAs).

    Palabras clave:
    PAD4citrulinaciónautoinmunidadcáncerproteómicaautoanticuerpos

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