Video Experimental Relacionado

Updated: Jan 18, 2026

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Published on: January 12, 2017

Valor pronóstico de la linfogammagrafía y SPECT/CT después de la transferencia de ganglios linfáticos vascularizados

Jeongmok Cho¹, Su Min Kim¹, Huisong Lee²

¹Department of Plastic and Reconstructive Surgery, Ewha Womans University Medical Center, Mokdong Hospital, Ewha Womans University College of Medicine.

Clinical nuclear medicine

|January 16, 2026

Abstracto

Background:

This study aimed to evaluate the prognostic value of postoperative lymphoscintigraphy and SPECT/CT in assessing clinical outcomes in lymphedema patients undergoing vascularized lymph node transfer (VLNT).

Patients And Methods:

Lymphedema patients who underwent VLNT between March 2019 and September 2023 were included in the study. All patients underwent postoperative lymphoscintigraphy 12 months after surgery. In addition to lymphoscintigraphy, SPECT/CT was performed during the later phase of the study period. Patient demographics, clinical stage, recipient site, and lymph node flap type, and lymphoscintigraphic findings were recorded and analyzed in relation to clinical outcomes.

Results:

Among the 57 extremities of 55 patients, postoperative lymphoscintigraphy showed positive radiotracer uptake in transferred lymph nodes in 31 extremities (54.4%). There were significantly higher rates of both subjective symptom improvement (77.4% vs 38.5%, P = 0.003) and Taiwan lymphoscintigraphy staging (TLS) grade improvement (55.6% vs 9.1%, P < 0.001) among patients with uptake compared with those without uptake. In addition, the frequency of cellulitis was significantly decreased in the uptake group (P = 0.010) but not in the non-uptake group (P = 0.211). A subset of 24 patients underwent SPECT/CT in addition to lymphoscintigraphy. Lymphoscintigraphic assessment revealed that 70% of patients with uptake achieved TLS grade improvement (P = 0.006). Spearman rank correlation analysis demonstrated a significant positive correlation between TLS grade improvement and SUVmax (correlation coefficient = 0.463, P = 0.045).

Conclusions:

Lymphoscintigraphy with SPECT/CT may serve as a valuable prognostic tool for evaluating surgical outcomes following VLNT in lymphedema treatment.

Palabras clave:

SPECT/CT imagen nuclear híbrida linfedema linfogammagrafía transferencia de ganglios linfáticos vascularizados (VLNT)

Más Videos Relacionados

Integrating Augmented Reality Tools in Breast Cancer Related Lymphedema Prognostication and Diagnosis

Integrating Augmented Reality Tools in Breast Cancer Related Lymphedema Prognostication and Diagnosis

Published on: February 6, 2020

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

Published on: November 2, 2019

Videos de Conceptos Relacionados

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...