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Updated: Jan 20, 2026

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AggrescanAI: Predicción de Regiones Propensas a la Agregación Utilizando Embeddings Contextualizados

Alvaro M Navarro¹, Santiago Palacios², Thierry Galmarini²

¹Fundación Instituto Leloir/IIBBA - CONICET, Buenos Aires, Argentina; Instituto Tecnológico de Buenos Aires (ITBA), Buenos Aires, Argentina.

Journal of molecular biology

|January 18, 2026

Resumen

AggrescanAI, una nueva herramienta de aprendizaje profundo, predice la propensión a la agregación de proteínas a partir de la secuencia solamente. Esto avanza la comprensión de las enfermedades neurodegenerativas y la ingeniería de proteínas al identificar regiones propensas a la agregación (APR).

Palabras clave:

Regiones propensas a la agregación Agregación de proteínas Modelos de lenguaje de proteínas Predicción basada en secuencia

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