Video Experimental Relacionado
Updated: Jan 23, 2026

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome
Published on: September 20, 2022
Metabolómica de Perfil Completo mediante GC-MS/MS Integrada en Enfermedades Cardiovasculares: Cuantificación Dirigida
Yasmin Elshoura1, Magy Herz1, Mohamed Z Gad2
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11835, Egypt.
Los ácidos grasos nitrados (NO2-FA) son moléculas de señalización clave. Un nuevo método GC-MS/MS mejoró el perfilado, encontrando NO2-OA elevado en pacientes con infarto de miocardio, lo que sugiere su potencial como biomarcador cardiovascular.
Conclusiones:
- El método GC-MS/MS desarrollado es altamente sensible y preciso para el perfilado de NO2-FA, utilizando derivatización de alquilación y un estándar interno innovador.
- Los niveles elevados de NO2-OA en pacientes con IAM sugieren su potencial como un nuevo biomarcador cardiovascular.
- Este enfoque metabolómico puede discriminar eficazmente entre grupos de pacientes y personas sanas, ayudando en el descubrimiento de biomarcadores para ECV.
Videos de Conceptos Relacionados
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Preparation of Amines: Reduction of Oximes and Nitro Compounds
Though catalytic hydrogenation can reduce nitrobenzenes, the reduction is nonselective in the presence of other functional groups. For instance, if nitrobenzene contains an aldehyde group,...
Gas Chromatography–Mass Spectrometry (GC–MS)
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
Overview of the Cardiovascular System
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
Acid Suppressive Drugs for Peptic Ulcer Disease: Antacids
However, this neutralization reaction between...

