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RM de cerebro para detectar lesiones críticas desmielinizantes de la médula espinal cervical en EM progresiva
Bianca Albites Coen1, Purnashree Chowdhury1, Steven A Messina2
1Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Journal of the neurological sciences
|January 22, 2026
Resumen
La RM de cerebro es insuficiente para detectar lesiones críticas de la médula espinal en la esclerosis múltiple (EM). Las imágenes dedicadas de la médula espinal son esenciales para el diagnóstico y seguimiento precisos de los pacientes con EM progresiva.
Área de la Ciencia:
- Neurología; Radiología; Imagenología Médica
Sus antecedentes:
- Las lesiones desmielinizantes críticas en la médula espinal cervical se relacionan con el deterioro motor progresivo en la esclerosis múltiple (EM).
Objetivo del estudio:
- Evaluar la eficacia de la RM de cerebro en la identificación de lesiones críticas de la médula espinal en pacientes con EM progresiva.
Principales métodos:
- Análisis retrospectivo de RM de cerebro de 65 pacientes con EM progresiva y lesiones en la médula espinal.
Principales resultados:
- La RM de cerebro fue 'informativa' en solo el 4,6% de los casos, y el 95,4% fueron 'incompletamente informativos'.
- La mayoría de los escaneos 'incompletamente informativos' no mostraron lesiones o solo las visualizaron en secuencias sagitales.
- Las secuencias MPRAGE y FLAIR mostraron cierta utilidad pero fueron insuficientes para una detección integral.
Conclusiones:
- La RM de cerebro es inadecuada para detectar lesiones desmielinizantes críticas de la médula espinal en la EM progresiva.
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