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Updated: Jan 24, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research

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Modelos animales de estenosis benigna de las vías respiratorias: Avances en técnicas de construcción, sistemas de

Wusheng Zhang¹, Yilin Chen¹, Chengcheng Yang¹

¹Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China.

Animal models and experimental medicine

|January 23, 2026

Abstract:

The incidence of benign airway stenosis (BAS) is on the rise, and current treatment options are associated with a significant risk of restenosis. Therefore, there is an urgent need to explore new and effective prevention and treatment methods. Animal models serve as essential tools for investigating disease mechanisms and assessing novel therapeutic strategies, and the scientific rigor of their construction and validation significantly impacts the reliability of research findings. This paper systematically reviews the research progress and evaluation systems of BAS animal models over the past decade, aiming to provide a robust foundation for the optimized construction of BAS models, intervention studies, and clinical translation. This effort is intended to facilitate the innovation and advancement in BAS prevention and treatment strategies.

Palabras clave:

estenosis de las vías respiratorias modelos animales estenosis benigna de las vías respiratorias sistemas de evaluación

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