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Updated: Jan 24, 2026

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Enfermedad atópica del compartimento central: Avances en patogénesis y tratamiento estratificado

Shaokun Huang^1,2, Xuan Shan³, Chaofan Li^1,2

¹Qinghai University Clinical Teaching Hospital, Qinghai University, China.

The Journal of international medical research

|January 23, 2026

Abstract:

Central compartment atopic disease is a recently delineated inflammatory endotype of chronic rhinosinusitis. It is characterized by involvement of the central intranasal compartment-the middle turbinate, superior turbinate, and posterior superior nasal septum-and is associated with a predominantly polypoid phenotype. This review synthesizes current evidence on local allergic pathophysiology, diagnostic frameworks, and stratified management of central compartment atopic disease to facilitate accurate diagnosis and individualized treatment.

Palabras clave:

Enfermedad atópica del compartimento central rinosinusitis crónica dinámica de fluidos computacional respuesta alérgica local deposición de partículas tratamiento personalizado

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