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Vitamina K en nutrición parenteral domiciliaria: ¿Es realmente necesaria?
Estrella Diego1, María Del Carmen Farnández1, Beatriz de León1
1Servicio de Endocrinología y Nutrición, H. U. Cruces, Barakaldo, Spain.
Endocrinologia, diabetes y nutricion
|January 23, 2026
Resumen
La adición de vitamina K a los multivitamínicos de nutrición parenteral provocó niveles elevados en el 80% de los pacientes. Se interrumpió el multivitamínico, normalizando los niveles de vitamina K en pacientes de nutrición parenteral domiciliaria.
Área de la Ciencia:
- Nutrición Clínica
- Manejo de Micronutrientes
- Terapia de Nutrición Parenteral
Sus antecedentes:
- La nutrición parenteral (NP) requiere una cobertura adecuada de micronutrientes, incluida la vitamina K, según las directrices de la ESPEN.
- Las preparaciones multivitamínicas con vitamina K añadida pretenden garantizar una ingesta suficiente en adultos que reciben NP.
Objetivo del estudio:
- Monitorizar los niveles de vitamina K en pacientes que reciben nutrición parenteral domiciliaria (NPD) tras la suplementación con un multivitamínico que contiene vitamina K.
- Evaluar el impacto de los multivitamínicos enriquecidos con vitamina K en el estado de vitamina K del paciente.
Principales métodos:
- Se analizaron los niveles de vitamina K en pacientes con NPD 6 meses después de iniciar un multivitamínico con vitamina K añadida.
- Estudio realizado en el Hospital Universitario Cruces entre 2021 y 2022, con 8 pacientes con fallo intestinal.
Principales resultados:
- El 80 % (6/8) de los pacientes con NPH presentaron niveles elevados de vitamina K (media 4,4 μl/L) tras la suplementación.
- Los pacientes presentaban fallo intestinal debido a síndrome del intestino corto, enfermedad mucosa o dismotilidad.
Conclusiones:
- La suplementación con un multivitamínico que contiene vitamina K provocó niveles supraterapéuticos de vitamina K en pacientes con NPD.
- La interrupción del multivitamínico enriquecido con vitamina K y la reanudación de los multivitamínicos convencionales normalizaron los niveles de vitamina K.
Palabras clave:
Fallo intestinalNutrición parenteral domiciliariaFallo intestinalNutrición parenteral domiciliariaVitamina KVitamina KMás Videos Relacionados
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