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Updated: Jan 25, 2026

Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes
Published on: January 12, 2024
Geometría del Complejo Ternario y Posicionamiento de Lisina Guían la Generación de Complejos Degradables Inducidos
Harish Kumar1, M Elizabeth Sobhia1
1Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
El diseño racional de PROTAC se avanza mediante un nuevo marco computacional que predice la eficiencia de la degradación de proteínas. Este método modela la geometría del complejo ternario y los efectos del enlazador, permitiendo el desarrollo de degradadores de proteínas dirigidos para enfermedades desafiantes.
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