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Factores Pronósticos de Supervivencia Global en el Ensayo VESPER: El Subtipo Molecular Basal es un Factor Clave
Christian Pfister1, Valentin Harter2, Jacqueline Fontugne3
1Department of Urology, Charles Nicolle University Hospital, Rouen, France; Onco-Urology Inserm Group 1404, Clinical Investigation Center, Rouen, France.
Cuatro factores, incluido el subtipo molecular basal, predicen la supervivencia global en pacientes con cáncer de vejiga músculo-invasivo que reciben quimioterapia neoadyuvante y cistectomía. La identificación de estos marcadores pronósticos mejora las predicciones de supervivencia.
Conclusiones:
- Se identificaron cuatro factores pronósticos clave para la SG en pacientes con CBMi tratados con QN en el ensayo VESPER.
- El subtipo molecular basal surgió como el factor pronóstico más significativo, independiente del brazo de tratamiento.
- Estos hallazgos resaltan la importancia de estos factores para mejorar la precisión pronóstica y potencialmente guiar las decisiones de tratamiento en CBMi.
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