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Transformación de las pruebas de coagulación: el papel de los biosensores en la medición del tiempo de protrombina
Induni Nayodhara Weerarathna1, Praveen Kumar2, Siah Kundy3
1Department of Biomedical Sciences, Datta Meghe Institute of Higher Education and Research Deemed to be university, Wardha, Maharashtra-442107, India.
ACS omega
|January 26, 2026
Resumen
Los biosensores ofrecen un enfoque revolucionario para las pruebas de tiempo de protrombina (TP), lo que permite una monitorización de la coagulación sanguínea más rápida, precisa y accesible. Estos avances prometen mejorar la atención al paciente a través de soluciones de pruebas en el punto de atención y en el hogar.
Área de la Ciencia:
- Ingeniería Biomédica; Diagnóstico Clínico; Nanotecnología
Sus antecedentes:
- El tiempo de protrombina (TP) es crucial para diagnosticar trastornos de la coagulación, controlar la terapia anticoagulante y evaluar la función hepática.; Las pruebas tradicionales de TP se basan en laboratorios centralizados, lo que plantea desafíos en cuanto a costo, tiempo y accesibilidad para muchos pacientes.; La tecnología de biosensores presenta una solución transformadora para superar las limitaciones de los métodos convencionales de prueba de TP.
Objetivo del estudio:
- Explorar los avances en la tecnología de biosensores para la monitorización del tiempo de protrombina (TP).; Discutir los principios fundamentales, los desarrollos actuales y las aplicaciones potenciales de los biosensores de TP.; Destacar la importancia de los biosensores en la mejora de la evaluación del TP y los resultados clínicos.
Principales métodos:
- Integración de microfluídica, nanotecnología y bio-MEMS para una monitorización precisa de la coagulación.; Desarrollo de dispositivos biosensores portátiles compatibles con plataformas de salud digital para el punto de atención (PoC) y el uso en el hogar.; Enfoque en estrategias para mejorar la sensibilidad, selectividad y rentabilidad en el diseño de biosensores de TP.
Principales resultados:
- Los biosensores facilitan la monitorización rápida, precisa y mínimamente invasiva de la coagulación.; Mayor utilidad en entornos de punto de atención y en el hogar debido a la portabilidad del dispositivo y la integración digital.; Potencial para la atención médica personalizada a través de una monitorización de la coagulación accesible e individualizada.
Conclusiones:
- Los biosensores son fundamentales para avanzar en la evaluación del TP, ofreciendo mejores resultados clínicos.; Estas tecnologías pueden revolucionar el diagnóstico al proporcionar soluciones de monitorización de la coagulación eficientes y asequibles.; La investigación continua y la colaboración interdisciplinaria son esenciales para aprovechar todo el potencial de los biosensores de TP en diversos entornos de atención médica.
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