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Enfermedad de Kikuchi-Fujimoto como Presentación Inicial de Dermatomiositis
Mohammad Mustafa1, Yasser Bawazir2
1Department of Medicine, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia.
Current rheumatology reviews
|January 27, 2026
Resumen
Este reporte de caso detalla la primera instancia documentada de la Enfermedad de Kikuchi-Fujimoto (EKF) como manifestación inicial de la dermatomiositis. El reconocimiento temprano y la terapia inmunosupresora personalizada son cruciales para manejar esta rara asociación.
Área de la Ciencia:
- Reumatología
- Inmunología
- Dermatología
Sus antecedentes:
- La Enfermedad de Kikuchi-Fujimoto (EKF) es una linfadenitis rara, típicamente autolimitada.
- La EKF puede asociarse ocasionalmente con condiciones autoinmunes.
- La dermatomiositis es una miopatía autoinmune caracterizada por debilidad muscular y erupción cutánea.
Objetivo del estudio:
- Reportar el primer caso documentado a nivel mundial de EKF como presentación inicial de dermatomiositis.
- Resaltar la novedad y rareza de este doble diagnóstico.
- Enfatizar la importancia de considerar enfermedades autoinmunes en la EKF refractaria.
Principales métodos:
- Estudio de caso de una mujer de 30 años con fiebre persistente, linfadenopatía y pérdida de peso.
- Diagnóstico de EKF confirmado mediante biopsia de ganglio linfático.
- Diagnóstico de dermatomiositis establecido a través de enzimas musculares elevadas, EMG, RM y erupción cutánea característica.
Principales resultados:
- El paciente se presentó inicialmente con síntomas compatibles con EKF.
- Investigaciones posteriores revelaron dermatomiositis concurrente.
- El paciente logró la remisión con pulsos de esteroides, IVIG y rituximab.
Conclusiones:
- Este caso subraya la necesidad de considerar la dermatomiositis en presentaciones atípicas o refractarias de EKF.
- El diagnóstico rápido y la terapia inmunosupresora apropiada son vitales para resultados favorables.
- Esta asociación, aunque rara, amplía el espectro conocido de comorbilidades de la EKF.
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