Video Experimental Relacionado
Updated: Jan 28, 2026
04:37
Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
1.3K
Terapia antibiótica oral para la infección periprotésica articular de hombro: conceptos actuales y en evolución
Christopher Fernainy1, Amritpal S Randhawa2, Matthew Frederickson2
1University of Nevada Reno School of Medicine, Reno, Nevada.
JB & JS open access
|January 27, 2026
Resumen
Los antibióticos orales muestran promesa para el tratamiento de la infección periprotésica articular (IPA) de hombro, ofreciendo una alternativa potencialmente menos onerosa a los antibióticos intravenosos (IV). Se necesitan ensayos de alta calidad para confirmar estos hallazgos para la IPA de hombro.
Área de la Ciencia:
- Cirugía Ortopédica
- Enfermedades Infecciosas
- Farmacología
Sus antecedentes:
- El tratamiento convencional para la infección periprotésica articular (IPA) de hombro implica antibióticos intravenosos (IV) prolongados a través de líneas centrales insertadas periféricamente (PICC).
- Este enfoque tradicional conlleva riesgos que incluyen infecciones relacionadas con el catéter, estancias hospitalarias prolongadas y aumento de los costos de atención médica.
- La evidencia reciente, incluido el ensayo OVIVA, sugiere que los antibióticos orales pueden ser tan efectivos como los antibióticos IV para infecciones ortopédicas complejas.
Objetivo del estudio:
- Evaluar el creciente cuerpo de evidencia sobre el uso de antibióticos orales para la IPA de hombro.
- Evaluar el potencial de la terapia antibiótica oral como una alternativa a los antibióticos IV en el manejo de la IPA de hombro.
- Destacar la necesidad de una mayor investigación para confirmar la eficacia y seguridad de los antibióticos orales en la IPA de hombro.
Principales métodos:
- Revisión de la literatura actual y estudios emergentes sobre terapia antibiótica oral para la IPA de hombro.
- Análisis de datos existentes, reconociendo que la mayoría de los estudios son pequeños y retrospectivos.
- Consideración de los hallazgos de ensayos como OVIVA sobre infecciones ortopédicas complejas.
Principales resultados:
- Datos limitados pero crecientes sugieren que la terapia antibiótica oral puede ser efectiva para la IPA de hombro en pacientes seleccionados.
- Los estudios existentes indican el potencial de resultados satisfactorios con regímenes de antibióticos orales.
- La base de evidencia actual se compone principalmente de investigaciones pequeñas y retrospectivas.
Conclusiones:
- La terapia antibiótica oral presenta una alternativa prometedora para el manejo de la IPA de hombro.
- La evidencia temprana apoya resultados satisfactorios en cohortes de pacientes específicas.
- Son esenciales ensayos multicéntricos de alta calidad para confirmar de manera definitiva la eficacia y seguridad de los antibióticos orales para la IPA de hombro.
Videos de Conceptos Relacionados
01:23Muscles of the Shoulder
9.1K
The muscles surrounding the shoulder girdle, including the clavicle and scapula, primarily stabilize the scapula. This stable base allows other muscles to move the humerus effectively. Scapular movements often mirror those of the humerus and extend its range of motion. For instance, raising the arm above the head would not be feasible without simultaneous upward rotation of the scapula.
Anterior Thoracic Muscles
The anterior thoracic muscles include the serratus anterior, subclavius, and...
Anterior Thoracic Muscles
The anterior thoracic muscles include the serratus anterior, subclavius, and...
9.1K
00:57Antibiotic Selection
59.9K
Overview
59.9K
01:16Structural Joints: Synovial Joints
6.7K
Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
6.7K
01:03Structural Joints: Fibrous Joints
3.7K
Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
3.7K
01:17Structural Joints: Cartilaginous Joints
4.0K
As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
4.0K
01:26Joints
35.6K
Joints, also called articulations or articular surfaces, are points at which ligaments or other tissues connect adjacent bones. Joints permit movement and stability, and can be classified based on their structure or function.
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
35.6K