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Una hoja de ruta integradora para avanzar en organoides de cáncer colorrectal

Youqing Zhu1, Ke He1, Zhi Shi1

  • 1Cancer Minimally Invasive Therapies Centre, Guangdong Second Provincial General Hospital, Department of Cell Biology & Institute of Biomedicine, Guangdong Provincial Biotechnology & Engineering Technology Research Center, Guangdong Provincial Key Laboratory of Bioengineering Medicine, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, Genomic Medicine Engineering Research Center of Ministry of Education, MOE Key Laboratory of Tumor Molecular Biology, National Engineering Research Center of Genetic Medicine, State Key Laboratory of Bioactive Molecules and Druggability Assessment, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Biomedicines
|January 28, 2026
PubMed
Resumen

Los organoides de cáncer colorrectal (CCRC) derivados de pacientes ofrecen modelos avanzados para el estudio del cáncer. La investigación futura necesita plataformas de próxima generación y herramientas computacionales para la terapia personalizada y la traducción clínica.

Palabras clave:
Organoide CCRCcribado de fármacosminicolonmulti-ómicasco-cultivo inmuno-organoidetratamiento personalizado

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