Estrés de Membrana y Ferroptosis: Dinámica Lipídica en el Cáncer

Jaewang Lee1,2, Youngin Seo3, Jong-Lyel Roh1,4

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Republic of Korea.

Resumen

Las células cancerosas se enfrentan a estrés osmótico por la peroxidación lipídica, un proceso relacionado con la ferroptosis (muerte celular dependiente de hierro). Los componentes de la membrana y los factores ambientales influyen en esta vía de muerte celular, ofreciendo posibles objetivos terapéuticos.

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