Video Experimental Relacionado
Updated: Jan 31, 2026
16:49
Multifocal Electroretinograms
Published on: December 4, 2011
18.9K
Electroretinograma de campo completo (ffERG) a los 48 meses se correlaciona con la disfunción retiniana basal en la
Fernanda Maria Silveira Souto1, Ruy Felippe Brito Gonçalves Missaka2, Marcelo Mendes Lavezzo2
1Department of Ophthalmology, Hospital das Clinicas, HCFMUSP, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. fernanda.souto@yahoo.com.br.
Documenta ophthalmologica. Advances in ophthalmology
|January 29, 2026
Resumen
Los parámetros del electroretinograma de campo completo (ffERG) en la enfermedad de Vogt-Koyanagi-Harada (VKH) mejoran en el primer año y se estabilizan. El ffERG persistentemente subnormal se correlaciona con una peor función basal y el desarrollo del fondo de ojo con brillo de atardecer.
Área de la Ciencia:
- Oftalmología
- Neurociencia
- Inmunología
Sus antecedentes:
- La enfermedad de Vogt-Koyanagi-Harada (VKH) es una afección inflamatoria sistémica que afecta al tracto uveal.
- El electroretinograma de campo completo (ffERG) es una herramienta diagnóstica clave para evaluar la función retiniana en diversas enfermedades oculares.
- Comprender la recuperación funcional a largo plazo en la enfermedad de VKH es crucial para el manejo del paciente.
Objetivo del estudio:
- Evaluar los parámetros del electroretinograma de campo completo (ffERG) en pacientes con enfermedad aguda de Vogt-Koyanagi-Harada (VKH).
- Evaluar las asociaciones clínicas de los parámetros de ffERG durante un período de seguimiento de 4 años.
- Investigar la relación entre la recuperación del ffERG y el desarrollo del fondo de ojo con brillo de atardecer (SGF).
Principales métodos:
- Estudio de cohorte retrospectivo de 21 pacientes con enfermedad aguda de VKH.
- Evaluaciones de ffERG realizadas en el momento basal, a los 6, 12 y 48 meses después de la inicio del tratamiento.
- Pacientes clasificados en ffERG normal (Grupo 1) y ffERG subnormal (Grupo 2) a los 48 meses.
Principales resultados:
- Mejora significativa en todos los parámetros de ffERG desde el inicio hasta los 12 meses, seguida de estabilización.
- El Grupo 2 (ffERG subnormal) mostró amplitudes consistentemente reducidas en comparación con el Grupo 1, a pesar de tendencias de recuperación similares.
- El fondo de ojo con brillo de atardecer (SGF) fue significativamente más frecuente en el Grupo 2 a los 12 meses (60,7%) frente al Grupo 1 (21,4%).
Conclusiones:
- La función retiniana en la enfermedad de VKH mejora en el primer año y se estabiliza posteriormente, independientemente de la modalidad de tratamiento.
- El ffERG persistentemente subnormal a los 48 meses indica una peor función retiniana basal.
- El ffERG subnormal se asocia con una mayor probabilidad de desarrollar SGF.
Más Videos Relacionados
Videos de Conceptos Relacionados
02:20Longitudinal Research
13.3K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.3K
01:26Longitudinal Studies
524
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
524
02:20Correlations
35.9K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
35.9K
01:27Correlation and Causation
42.5K
Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
42.5K
01:09Correlation
15.1K
In statistics, two variables are said to be correlated if the values of one variable are associated with the other variable. Depending on the relationship between two variables, correlation can be of three types– positive correlation, negative correlation, and zero correlation.
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
15.1K
00:53Correlation and Regression
3.4K
In statistics, correlation describes the degree of association between two variables. In the subfield of linear regression, correlation is mathematically expressed by the correlation coefficient, which describes the strength and direction of the relationship between two variables. The coefficient is symbolically represented by 'r' and ranges from -1 to +1. A positive value indicates a positive correlation where the two variables move in the same direction. A negative value suggests a...
3.4K