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Updated: Feb 3, 2026

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Análisis cuantitativo de los patrones de truncamiento del genoma en vectores de virus adenoasociados
Yifan Yang1, Dongxin Wang1, Yun Yuan1
1Suzhou Institute of Biomedical Engineering and Technology, CAS No.88, Keling Road, Suzhou, 215163, Jiangsu, People's Republic of China.
Biotechnology letters
|February 1, 2026
Resumen
El empaquetado del vector del virus adenoasociado (AAV) trunca genomas grandes, y se produce una pérdida significativa de ADN más allá de los 4,5 kb. Esto afecta el diseño del vector de terapia génica y la expresión del gen reportero.
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