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Osteoma coroideo complicado con neovascularización coroidea: reporte de un caso

Aisha Ahmed Khan¹, Zaid Azhar¹, Muhammad Amer Awan^1,2

¹Ophthalmology, Shifa International Hospital Islamabad, Islamabad, PAK.

|February 2, 2026

Resumen

Se trató con éxito un osteoma coroideo pediátrico complicado con neovascularización coroidea (CNV) mediante inyecciones intravítreas de anti-factor de crecimiento endotelial vascular (anti-VEGF). Este tratamiento condujo a una regresión significativa de la CNV y del líquido subretiniano, mejorando la visión.

Área de la Ciencia:

Oftalmología
Imagen Médica
Oncología

Sus antecedentes:

El osteoma coroideo es un tumor raro y benigno de la coroides, osificado.
La neovascularización coroidea (CNV) puede complicar los osteomas coroideos, provocando pérdida de visión.
Los casos pediátricos de osteoma coroideo con CNV son poco comunes y requieren estrategias de manejo específicas.

Objetivo del estudio:

Informar sobre el manejo exitoso de un caso pediátrico de osteoma coroideo con neovascularización coroidea (CNV) asociada.
Evaluar la eficacia de la terapia intravítrea con anti-factor de crecimiento endotelial vascular (anti-VEGF) en un paciente pediátrico con CNV secundaria a osteoma coroideo.
Destacar la importancia de la imagen multimodal en el diagnóstico y seguimiento de esta rara afección.

Principales métodos:

Una niña de 13 años presentó visión borrosa secundaria a osteoma coroideo.
El diagnóstico se confirmó mediante examen de fondo de ojo, ultrasonografía modo B y tomografía de coherencia óptica de fuente de barrido (SS-OCT).
El tratamiento incluyó un curso de nueve meses de inyecciones intravítreas de anti-VEGF, junto con imágenes multimodales para el seguimiento.

Principales resultados:

Las inyecciones intravítreas de anti-VEGF resultaron en una regresión significativa de la neovascularización coroidea (CNV).
Se observó una reducción notable del líquido subretiniano (SRF) después del tratamiento.
El paciente demostró resultados anatómicos y funcionales favorables con monitorización continua y terapia intermitente.

Conclusiones:

La terapia intravítrea con anti-VEGF es un tratamiento eficaz para la neovascularización coroidea pediátrica secundaria a osteoma coroideo.
La imagen multimodal juega un papel crucial en el diagnóstico, manejo y seguimiento de tales casos.
El tratamiento rápido puede conducir a una mejora visual significativa y estabilización en pacientes con esta rara afección.

Palabras clave:

tratamiento anti-VEGF calcificación coroides neovascularización coroidea osteoma coroideo inyecciones intravítreas OCT de fuente de barrido (SS-OCT)

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