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Meningoencefalitis Criptocócica en un Paciente Inmunocompetente: Un Informe de Caso
Kailie A McGee1, Pardis A Zarandi1, Sanjna Tripathy1
1Internal Medicine, Baylor Scott & White All Saints Medical Center, Fort Worth, USA.
Cureus
|February 2, 2026
Resumen
La meningoencefalitis criptocócica (MC) puede ser difícil de diagnosticar en personas inmunocompetentes. El reconocimiento temprano y el tratamiento antifúngico son cruciales para prevenir complicaciones neurológicas graves.
Área de la Ciencia:
- Enfermedades Infecciosas; Neurología; Micología
Sus antecedentes:
- La meningoencefalitis criptocócica (MC) es una infección fúngica grave que afecta el sistema nervioso central.; El diagnóstico puede retrasarse en pacientes inmunocompetentes debido a síntomas inespecíficos.
Objetivo del estudio:
- Destacar los desafíos diagnósticos de la MC en un paciente inmunocompetente.; Enfatizar la importancia de considerar la meningitis fúngica en presentaciones de dolor de cabeza atípico.
Principales métodos:
- Informe de caso de una mujer inmunocompetente de 25 años con sospecha de MC.; Las investigaciones iniciales, incluido el análisis del LCR y las imágenes, no fueron concluyentes.; Diagnóstico confirmado por pruebas positivas de antígeno de Cryptococcus en suero.
Principales resultados:
- La paciente presentó dolor de cabeza intenso, fiebre y signos meníngeos.; El análisis del líquido cefalorraquídeo mostró una presión de apertura elevada pero recuentos celulares y química normales.; La prueba de antígeno de Cryptococcus en suero fue clave para el diagnóstico, revelando una exposición inusual a aves de corral de traspatio.
Conclusiones:
- El diagnóstico de MC en personas inmunocompetentes requiere un alto índice de sospecha.; Los dolores de cabeza persistentes o atípicos justifican la consideración de meningitis fúngica.; La terapia antifúngica rápida es vital para resultados favorables y para prevenir secuelas neurológicas.
Palabras clave:
dolor de cabeza atípicomeningitis criptocócica (mc)meningoencefalitis criptocócicameningoencefalitis criptocócica por cryptococcus neoformans/gattiipunción lumbar fúngicameningitis fúngicaadulto inmunocompetenteMás Videos Relacionados
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