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Hipercalcemia Aguda Resultante de Microesferas de Sulfato de Calcio Impregnadas con Antibióticos
Bryan Lopez1, Vindeep Bhandari1, Guilianne R Servano1
1Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, USA.
Cureus
|February 2, 2026
Resumen
Un paciente desarrolló hipercalcemia después de recibir microesferas de sulfato de calcio durante la cirugía de cadera por infección. Este caso destaca un efecto secundario poco común de las microesferas de sulfato de calcio utilizadas en procedimientos ortopédicos.
Área de la Ciencia:
- Cirugía Ortopédica
- Nefrología
- Endocrinología
Sus antecedentes:
- Una fractura de cadera llevó a la artroplastia total de cadera (THA) en un hombre de 86 años con enfermedad renal crónica.
- La infección de la prótesis articular durante la THA requirió desbridamiento, antibióticos y retención del implante (DAIR).
- Se utilizaron microesferas de sulfato de calcio (CSB) durante el procedimiento DAIR.
Objetivo del estudio:
- Informar un caso de hipercalcemia después del uso de CSB en cirugía ortopédica.
- Destacar un efecto adverso poco común asociado con los CSB.
Principales métodos:
- Un paciente se sometió a DAIR por infección de la prótesis articular después de THA.
- Se colocaron CSB durante el procedimiento quirúrgico.
- La hipercalcemia se desarrolló posoperatoriamente y se trató con fluidos IV, diuréticos y calcitonina.
Principales resultados:
- El paciente desarrolló hipercalcemia significativa después de la colocación de CSB.
- El tratamiento para la hipercalcemia incluyó reanimación con líquidos, diuresis y administración de calcitonina.
- La hipercalcemia se resolvió con tratamiento médico.
Conclusiones:
- La hipercalcemia es una complicación potencial, aunque poco común, del uso de CSB en cirugía ortopédica.
- Los médicos deben ser conscientes de este efecto adverso al utilizar CSB.
- Puede ser recomendable la monitorización de los niveles de calcio en pacientes tratados con CSB.
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