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Bernoulli's Principle: Applications01:17

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There are many devices and situations in which fluid flows at a constant height and so can be analyzed using Bernoulli's principle. These devices include, but are not limited to, entrainment devices and fluid flow measuring devices.
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Design Example: Application of Archimedes' Principle01:11

Design Example: Application of Archimedes' Principle

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Archimedes' principle is fundamental in analyzing the buoyant force and stability of floating bodies. In this example, a wooden block with a rectangular section floats in seawater. Based on the block's dimensions, its specific gravity and the specific weight of seawater are used to find the volume of water displaced and the center of buoyancy.
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The Uncertainty Principle04:08

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Werner Heisenberg considered the limits of how accurately one can measure properties of an electron or other microscopic particles. He determined that there is a fundamental limit to how accurately one can measure both a particle’s position and its momentum simultaneously. The more accurate the measurement of the momentum of a particle is known, the less accurate the position at that time is known and vice versa. This is what is now called the Heisenberg uncertainty principle. He...
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Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
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The Pauli Exclusion Principle03:06

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The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information:
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The Aufbau Principle and Hund's Rule03:02

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To determine the electron configuration for any particular atom, we can build the structures in the order of atomic numbers. Beginning with hydrogen, and continuing across the periods of the periodic table, we add one proton at a time to the nucleus and one electron to the proper subshell until we have described the electron configurations of all the elements. This procedure is called the aufbau principle, from the German word aufbau (“to build up”). Each added electron occupies the...
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SlipChip: del principio a las aplicaciones

Yang Luo1, Weijie Yuan2, Sujin Jung1

  • 1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. feng.shen@sjtu.edu.cn.

Lab on a chip
|February 4, 2026
PubMed
Resumen
Este resumen es generado por máquina.

La SlipChip es una plataforma microfluídica que permite un control preciso de fluidos mediante placas deslizantes, simplificando ensayos complejos. Esta tecnología versátil ofrece portabilidad y rentabilidad para diversas aplicaciones en investigación y diagnóstico.

Palabras clave:
microfluídicaSlipChipdiagnósticoinvestigaciónlab-on-a-chip

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Área de la Ciencia:

  • Biotecnología e Ingeniería Biomédica
  • Tecnología Microfluídica y Lab-on-a-Chip

Sus antecedentes:

  • Las plataformas microfluídicas son cruciales para el manejo preciso de fluidos en diversas disciplinas científicas.
  • La microfluídica convencional a menudo requiere componentes externos complejos como bombas y válvulas.
  • La SlipChip ofrece un enfoque novedoso para el control microfluídico a través de la reconfiguración mecánica.

Objetivo del estudio:

  • Revisar los principios de fluidos, métodos de fabricación y diversas aplicaciones de la plataforma SlipChip.
  • Destacar las ventajas de SlipChip sobre los sistemas microfluídicos convencionales.
  • Analizar las limitaciones actuales y los avances futuros en la tecnología SlipChip.

Principales métodos:

  • Revisión de la literatura existente sobre el diseño, principios y aplicaciones de SlipChip.
  • Análisis de los mecanismos de reconfiguración de fluidos inducidos por placas deslizantes.
  • Examen de las consideraciones de materiales para la fabricación de SlipChip.

Principales resultados:

  • SlipChip permite la alícuota, mezcla y partición precisa de fluidos mediante simples operaciones de deslizamiento.
  • Las aplicaciones abarcan ensayos de ácidos nucleicos, análisis de proteínas, estudios de células únicas y síntesis de materiales.
  • Las ventajas incluyen manipulación simple, precarga de reactivos en el chip, portabilidad y fabricación rentable.

Conclusiones:

  • SlipChip es una plataforma microfluídica robusta y accesible con un potencial significativo para la investigación y el diagnóstico clínico.
  • Los desarrollos futuros en materiales, automatización e IA mejorarán la fiabilidad y permitirán flujos de trabajo autónomos.
  • La tecnología está preparada para expandir su papel en biología de sistemas, diagnóstico y medicina personalizada.