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Vitaminas y nutracéuticos en la investigación del glaucoma
Flora Hui1, Pete A Williams1,2
1Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
European journal of ophthalmology
|February 4, 2026
Resumen
Los nutracéuticos muestran promesa para proteger la visión en pacientes con glaucoma al apoyar las células retinianas y potencialmente reducir la presión ocular. Esta revisión examina 35 suplementos, evaluando su efectividad para el manejo del glaucoma.
Área de la Ciencia:
- Oftalmología
- Neurociencia
- Ciencia de la Nutrición
Sus antecedentes:
- El glaucoma es una causa principal de ceguera irreversible a nivel mundial.
- El manejo actual se centra en reducir la presión intraocular, un factor de riesgo modificable clave.
- Se investigan los nutracéuticos por su potencial para proteger las células ganglionares de la retina y la degeneración del nervio óptico.
Objetivo del estudio:
- Revisar exhaustivamente la investigación más reciente sobre 35 vitaminas, minerales y nutracéuticos para el glaucoma.
- Analizar los mecanismos de acción propuestos para estos compuestos.
- Informar sobre sus efectos en la salud de las células ganglionares de la retina y en pacientes con glaucoma.
Principales métodos:
- Revisión sistemática de la evidencia científica.
- Análisis de los mecanismos de acción propuestos para diversos nutracéuticos.
- Evaluación de los efectos reportados sobre la salud de las células ganglionares de la retina y los resultados del glaucoma.
Principales resultados:
- Niveles variables de evidencia respaldan el uso de nutracéuticos específicos en el glaucoma.
- Los suplementos que aumentan el NAD y los antioxidantes muestran potencial para apoyar el metabolismo de las células retinianas y reducir el estrés oxidativo.
- Las terapias combinadas pueden ofrecer beneficios sinérgicos para la neuroprotección en el glaucoma.
Conclusiones:
- Los nutracéuticos representan una terapia adyuvante potencial para el glaucoma, dirigida a vías metabólicas y neurodegenerativas.
- Se necesita más investigación para establecer la eficacia definitiva y el uso óptimo de estos compuestos.
- Las estrategias nutricionales personalizadas pueden desempeñar un papel en la preservación de la visión en pacientes con glaucoma.
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