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Updated: Feb 7, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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2-Aminobenzotiazol: Un Andamio Privilegiado para Agentes Anticancerígenos Dirigidos a Tirosina Quinasa

Rani D Navle1, Nirmala V Shinde1, Arti S Raut1

  • 1Department of Pharmaceutical Chemistry, SMBT College of Pharmacy, Nashik, India.

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
|February 6, 2026
PubMed
Resumen

Los derivados de 2-aminobenzotiazol muestran promesa como agentes anticancerígenos, dirigidos a quinasas como CDK y EGFR, y dianas no quinasas como BCL-2. La investigación en química medicinal se enfoca en optimizar sustituciones para mejorar la eficacia y especificidad en terapias contra el cáncer dirigidas.

Palabras clave:
2-AminobenzotiazolAgentes anticancerígenosDiseño de fármacosAndamios heterocíclicosSeñalización de quinasasRelación estructura-actividad (SAR)Terapia contra el cáncer dirigidaInhibidores de tirosina quinasaInhibición de VEGFR-2/EGFR

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