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Updated: Feb 7, 2026

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
Dar forma al microambiente tumoral: perspectivas de las interacciones huésped-microbiota
Khiem C Lam1,2, Romina S Goldszmid1
1Laboratory of Integrative Cancer Immunology (LICI), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.
Abstract:
Gut microbiota has emerged as a determinant of cancer therapy efficacy, shaping immune responses both systemically and locally within the tumor microenvironment. In this piece, we discuss current insights into the mechanistic basis of these interactions, with a focus on type I interferon as a central mediator of microbiota-driven immune modulation.
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