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Establecimiento de estándares: armonización de principios de codificación para un conjunto de datos mínimo de cáncer

A Ajmal¹, O Bouissou², J Brash¹

¹IQVIA Ltd, London, UK.

ESMO real world data and digital oncology

|February 6, 2026

Resumen

El marco de Descripción Esencial Mínima del Cáncer (MEDOC) estandariza los datos oncológicos para el análisis de redes. Esta herramienta compatible con OMOP CDM mejora la solidez de la investigación al abordar la heterogeneidad de datos en la Red Oncológica Digital para Europa (DigiONE).

Área de la Ciencia:

Oncología
Informática de la Salud
Estandarización de Datos

Sus antecedentes:

El análisis de datos clínicos en redes enfrenta desafíos debido a la heterogeneidad de los datos.
El Modelo de Datos Común (CDM) de Observational Medical Outcomes Partnership (OMOP) ofrece un marco estandarizado para datos clínicos.
La estandarización mejora el poder analítico y la solidez de la investigación en estudios multicéntricos.

Objetivo del estudio:

Desarrollar un marco para capturar información oncológica específica dentro del OMOP CDM.
Facilitar las comparaciones a nivel de red y la combinación de datos para la Red Oncológica Digital para Europa (DigiONE).
Abordar los desafíos de la heterogeneidad de datos en la investigación oncológica europea.

Principales métodos:

El marco de Descripción Esencial Mínima del Cáncer (MEDOC) se desarrolló a través de procesos iterativos impulsados por la comunidad.
Se llevaron a cabo sesiones de inmersión profunda para alinear los datos de origen con la estructura MEDOC.
MEDOC se utilizó en estudios piloto dentro de la red DigiONE.

Principales resultados:

La versión inicial de MEDOC se ha aplicado a dos estudios observacionales de cáncer de DigiONE, con dos más en curso.
Se han desarrollado recursos de capacitación y una guía de implementación para MEDOC.
Se identificaron desafíos en la alineación de la granularidad de los datos para la fecha de diagnóstico, la ubicación de la metástasis y la clasificación del tumor.

Conclusiones:

El marco MEDOC demuestra utilidad en aplicaciones de investigación y se desarrollará continuamente.
La alineación con el OMOP CDM es oportuna, apoyando las iniciativas europeas para la armonización de datos de salud.
El desarrollo futuro incorporará los aprendizajes de los centros participantes y los avances en oncología.

Palabras clave:

Modelo de Datos Común (CDM)Observational Health Data Sciences and Informatics (OHDSI)Observational Medical Outcomes Partnership (OMOP)investigación sobre el cáncer

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