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Enfermedad Venooclusiva Pulmonar: Una Pista de Linfoma Subyacente
Chaynez Rachid1, Othman Abouobayd1, Mohamed Ijim1
1Pulmonology, Morpho-Sciences Research Laboratory, Faculty of Medicine and Pharmacy of Marrakech, Cadi Ayyad University, Arrazi Hospital, University Hospital Center Mohammed VI, Marrakech, MAR.
Cureus
|February 6, 2026
Resumen
La enfermedad venooclusiva pulmonar (PVOD) puede ser un signo raro de linfoma. El diagnóstico temprano es crucial, ya que los tratamientos estándar para la hipertensión pulmonar pueden ser perjudiciales en la PVOD asociada a malignidad.
Área de la Ciencia:
- Cardiología
- Oncología
- Neumología
Sus antecedentes:
- La enfermedad venooclusiva pulmonar (PVOD) es una causa rara de hipertensión pulmonar postcapilar, distinta de la hipertensión arterial pulmonar (HAP).
- La PVOD puede ser idiopática, genética o secundaria a otras afecciones, incluidas neoplasias malignas ocultas como el linfoma.
Objetivo del estudio:
- Informar un caso de PVOD que se presenta como un síntoma de linfoma de Hodgkin.
- Destacar la importancia de considerar la malignidad en pacientes con PVOD y linfadenopatía.
Principales métodos:
- Informe de caso de un paciente de 31 años con disnea progresiva y signos de insuficiencia cardíaca derecha.
- La tomografía computarizada torácica inicial reveló hallazgos característicos de PVOD y linfadenopatía mediastínica.
- La biopsia de ganglios linfáticos axilares confirmó el linfoma de Hodgkin.
Principales resultados:
- El paciente presentó signos radiológicos sugestivos de PVOD.
- La biopsia de ganglios linfáticos confirmó el linfoma de Hodgkin, lo que indica que la PVOD es un fenómeno secundario.
- No se realizó cateterismo cardíaco derecho debido al deterioro clínico.
Conclusiones:
- La PVOD requiere alta sospecha clínica, especialmente cuando se acompaña de linfadenopatía.
- Es obligatorio un estudio exhaustivo del linfoma en tales casos.
- Diferenciar la PVOD primaria de la PVOD asociada a malignidad es fundamental debido a posibles complicaciones fatales con los vasodilatadores pulmonares estándar.
Palabras clave:
opacidades difusas en vidrio deslustradolinfoma de Hodgkinlinfadenopatíahipertensión pulmonar postcapilarPVODMás Videos Relacionados
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