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Updated: Feb 7, 2026
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Murine Ileocolic Bowel Resection with Primary Anastomosis
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Resección intestinal masiva para niños con insuficiencia intestinal no del síndrome del intestino corto
F Y Takamatsu1,2, P Wales1,3,4, C Belza1,2
1Group for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, Toronto, Canada.
Intestinal Failure (New York, N.Y.)
|February 6, 2026
Resumen
La resección intestinal extensa puede controlar los síntomas en pacientes pediátricos con insuficiencia intestinal con pseudo-obstrucción intestinal crónica (CIPO) y enfermedad de inclusión de microvellosidades (MVID). Este enfoque reduce las necesidades de nutrición parenteral y mejora la calidad de vida.
Área de la Ciencia:
- Cirugía Pediátrica
- Gastroenterología
- Manejo de la Insuficiencia Intestinal
Sus antecedentes:
- Los pacientes pediátricos con pseudo-obstrucción intestinal crónica (CIPO) y diarreas congénitas y enteropatías (CODE) representan poblaciones únicas de insuficiencia intestinal (II).
- El trasplante intestinal a menudo se considera para estos casos complejos.
- Se explora la resección intestinal extensa como modalidad de tratamiento alternativa.
Objetivo del estudio:
- Describir la resección intestinal extensa como tratamiento para el control de los síntomas en CIPO y enfermedad de inclusión de microvellosidades (MVID).
- Evaluar el impacto de este enfoque quirúrgico en los requisitos de nutrición parenteral (NP) y la calidad de vida.
Principales métodos:
- Estudio de caso de dos pacientes pediátricos con distintas afecciones de II: MVID y CIPO.
- El Paciente 1 (MVID) se sometió a una resección extensa de yeyunoileon y colectomía subtotal.
- El Paciente 2 (CIPO) se sometió a una enterectomía parcial con estrechamiento para complicaciones del estoma.
Principales resultados:
- Tras la resección, el Paciente 1 mostró una reducción significativa del volumen de NP y las necesidades de electrolitos, con una mejora de la calidad de vida.
- El Paciente 2 experimentó la resolución de complicaciones del estoma y obstrucción intestinal durante cuatro años después de la cirugía.
- Ambos pacientes demostraron una mejora del manejo y una reducción de la morbilidad tras la enterectomía extensa.
Conclusiones:
- La enterectomía extensa es una opción quirúrgica viable no trasplantable para el control de los síntomas en pacientes seleccionados con II.
- Este enfoque puede mejorar la calidad de vida, reducir la morbilidad y facilitar el manejo de la NP.
- La consideración de la resección extensa puede ser beneficiosa para pacientes con CIPO o enteropatías mucosas refractarias al tratamiento médico.
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